BDBM50219117 CHEMBL244562::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-trans-but-2-enyl)-4-(6-oxo-1,6-dihydropyridin-2-yl)benzamide::US8748608, 9

SMILES Clc1cccc(N2CCN(C\C=C\CNC(=O)c3ccc(cc3)-c3cccc(=O)[nH]3)CC2)c1Cl

InChI Key InChIKey=GTRAXVNCZVAHOO-OWOJBTEDSA-N

Data  6 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219117   

TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219117(CHEMBL244562 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  23.6nMAssay Description:Displacement of [125I]IABN from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219117(CHEMBL244562 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50219117(CHEMBL244562 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataIC50:  41nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In DepthDetails US Patent